Magnetic resonance imaging methods for study of human brain function and their application at high magnetic field.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society · 1996 · Unclear · Insufficient evidence

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UnclearInsufficient evidencePaper 4259

The article overviews MRI sequences used to study human brain function by monitoring localized signal intensity changes accompanying neuronal activity, including sequences sensitized to cerebral blood volume, blood flow, and blood oxygenation. It notes that m…

Study snapshot

PublicationComputerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society · 1996
Study typereview
Reported directionUnclear
Evidence ratingInsufficient

Abstract

Magnetic resonance imaging (MRI) sequences are finding a new application in the study of human brain function by monitoring localized changes in signal intensity which accompany neuronal activity. These sequences can be sensitized to changes in cerebral blood volume, cerebral blood flow, and blood oxygenation, all of which reflect aspects of neuronal activity in the brain. Many of these experiments benefit from being implemented at a higher magnetic field strength than conventional MRI. An overview of these techniques is presented, and examples of their use are given.

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typereview
Effect directionunclear
PopulationHumans
Sample sizeNot supplied
ExposureNot supplied
Evidence strengthInsufficientConfidence: 66% · Peer reviewed: yes

Main findings

The article overviews MRI sequences used to study human brain function by monitoring localized signal intensity changes accompanying neuronal activity, including sequences sensitized to cerebral blood volume, blood flow, and blood oxygenation. It notes that many such experiments benefit from implementation at higher magnetic field strength than conventional MRI and provides examples of use.

Outcomes measured

  • MRI signal intensity changes associated with neuronal activity
  • Cerebral blood volume
  • Cerebral blood flow
  • Blood oxygenation
View raw extracted JSON
{
  "study_type": "review",
  "exposure": {
    "band": null,
    "source": "MRI (high magnetic field strength)",
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": null
  },
  "population": "Humans",
  "sample_size": null,
  "outcomes": [
    "MRI signal intensity changes associated with neuronal activity",
    "Cerebral blood volume",
    "Cerebral blood flow",
    "Blood oxygenation"
  ],
  "main_findings": "The article overviews MRI sequences used to study human brain function by monitoring localized signal intensity changes accompanying neuronal activity, including sequences sensitized to cerebral blood volume, blood flow, and blood oxygenation. It notes that many such experiments benefit from implementation at higher magnetic field strength than conventional MRI and provides examples of use.",
  "effect_direction": "unclear",
  "limitations": [],
  "evidence_strength": "insufficient",
  "confidence": 0.66,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "MRI",
    "functional MRI",
    "brain function",
    "neuronal activity",
    "signal intensity",
    "cerebral blood volume",
    "cerebral blood flow",
    "blood oxygenation",
    "high magnetic field"
  ],
  "suggested_hubs": [
    {
      "slug": "mri-static-fields",
      "weight": 0.78,
      "reason": "Discusses MRI methods and benefits of higher magnetic field strength."
    }
  ]
}
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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1016/s0895-6111(96)00044-4
PubMed: 9007214

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