[Late effects of radiofrequency fulguration: report of five cases].
← Research streamFive patients had apparent acute failure after radiofrequency fulguration (persistent conduction, inducible tachycardia, or recurrence during follow-up), but repeat electrophysiological study showed fulguration had been effective in all cases. Authors attribu…
Study snapshot
Abstract
Radiofrequency fulguration is the definitive treatment of several supraventricular and ventricular arrhythmias. During radiofrequency application, the conduction in a specific zone is interrupted as a consequence of cellular necrosis and edema. The disappearance of edema, minutes or hours after the procedure, allows the reappearance of conduction and arrhythmias. On the other hand, the definitive lesion is larger than the one caused acutely, due to the progression of the scar. We report five patients, in whom there was an apparent failure of the fulguration, since at the end of the procedure there was conduction in the fulgurated zone, the tachycardia was inducible or pre excitation and arrhythmias reappeared during the follow up. All five were subjected to a new electrophysiological study and in all, fulguration had been effective. We conclude that these late effects of fulguration are due to the slow progression of fibrosis, that continues days or weeks after the procedure.
AI evidence extraction
Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.
Main findings
Five patients had apparent acute failure after radiofrequency fulguration (persistent conduction, inducible tachycardia, or recurrence during follow-up), but repeat electrophysiological study showed fulguration had been effective in all cases. Authors attribute the late effects to slow progression of fibrosis over days to weeks after the procedure.
Outcomes measured
- Conduction in fulgurated zone at end of procedure
- Inducibility/recurrence of tachycardia or arrhythmias during follow-up
- Effectiveness of fulguration on repeat electrophysiological study
- Late fibrosis/scar progression
Limitations
- Case report series with five patients
- No quantitative exposure parameters (frequency, power, SAR, duration) reported in abstract
- No control/comparator group described
- Follow-up duration and patient characteristics not specified in abstract
View raw extracted JSON
{
"study_type": "case_report",
"exposure": {
"band": null,
"source": "radiofrequency fulguration (catheter ablation)",
"frequency_mhz": null,
"sar_wkg": null,
"duration": null
},
"population": "Patients treated with radiofrequency fulguration for arrhythmias (supraventricular/ventricular)",
"sample_size": 5,
"outcomes": [
"Conduction in fulgurated zone at end of procedure",
"Inducibility/recurrence of tachycardia or arrhythmias during follow-up",
"Effectiveness of fulguration on repeat electrophysiological study",
"Late fibrosis/scar progression"
],
"main_findings": "Five patients had apparent acute failure after radiofrequency fulguration (persistent conduction, inducible tachycardia, or recurrence during follow-up), but repeat electrophysiological study showed fulguration had been effective in all cases. Authors attribute the late effects to slow progression of fibrosis over days to weeks after the procedure.",
"effect_direction": "unclear",
"limitations": [
"Case report series with five patients",
"No quantitative exposure parameters (frequency, power, SAR, duration) reported in abstract",
"No control/comparator group described",
"Follow-up duration and patient characteristics not specified in abstract"
],
"evidence_strength": "very_low",
"confidence": 0.74,
"peer_reviewed_likely": "yes",
"keywords": [
"radiofrequency fulguration",
"catheter ablation",
"arrhythmia",
"tachycardia",
"fibrosis",
"scar progression",
"late effects",
"electrophysiological study"
],
"suggested_hubs": []
}AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.
Identifiers and source
DOI: Not supplied
PubMed: 10349164
Related papers
- Radiofrequency Pulmonary Vein Isolation in a Patient with Dextrocardia With Situs Inversus Totalis. 2017
- The effects of electrode-tissue contact on radiofrequency lesion generation. 1997
- Lack of evidence of areas of slow conduction early after radiofrequency current application at porcine atrial myocardium. 1996
- [Management of nodal reentrant tachycardia with radiofrequency: predictive criteria of success]. 1995
- [Radiofrequency treatment of tachyarrhythmias in children and adolescents]. 1995
- The induction of reentry in cardiac tissue. The missing link: How electric fields alter transmembrane potential. 1998