[Use of super-high frequency electromagnetic fields on intrarenal circulation and morphological status of health kidneys (experimental study)].

{
  "study_type": "animal",
  "exposure": {
    "band": "RF",
    "source": null,
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": null
  },
  "population": "Female rats (healthy kidneys)",
  "sample_size": null,
  "outcomes": [
    "Intrarenal circulation/hemodynamics",
    "Renal morphology (stromal edema, tubular epithelial dystrophy, periglomerular sclerosis)",
    "Aseptic interstitial inflammation",
    "Prostaglandin E2 levels in renal papilla tissue"
  ],
  "main_findings": "In female rats, decimetric electromagnetic waves produced a marked hemodynamic effect with redistribution of intrarenal circulation. Exposure at 395 mW/cm2 was associated with dysregulation of intrarenal blood flow and morphological changes including hemodynamic disorders, flebostasis, stromal edema, tubular epithelial dystrophy, and periglomerular sclerosis with aseptic interstitial inflammation; prostaglandin E2 levels in renal papilla tissue were reported as supporting evidence.",
  "effect_direction": "harm",
  "limitations": [
    "Sample size not reported in abstract",
    "Exposure frequency and duration not reported in abstract",
    "Animal study; generalizability to humans not established in abstract",
    "Details of experimental design (controls, randomization, blinding) not reported in abstract"
  ],
  "evidence_strength": "low",
  "confidence": 0.74,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "decimetric waves",
    "super-high frequency electromagnetic fields",
    "rats",
    "kidney",
    "intrarenal circulation",
    "hemodynamics",
    "renal morphology",
    "prostaglandin E2",
    "interstitial inflammation"
  ],
  "suggested_hubs": [
    {
      "slug": "rf-health-effects",
      "weight": 0.7,
      "reason": "Animal experiment assessing renal functional and morphological effects of RF (decimetric) electromagnetic waves."
    }
  ]
}