[Electric field effect of cell calcium].

{
  "study_type": "in_vitro",
  "exposure": {
    "band": "ELF",
    "source": null,
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": null
  },
  "population": "HL-60 leukemia cells",
  "sample_size": null,
  "outcomes": [
    "Ca2+ transport/flux through plasma membrane ion channels",
    "intracellular calcium levels"
  ],
  "main_findings": "The paper discusses effects of an externally applied signal (Vi = 30 sin 100 pi t mV) on induced Ca2+ flux in HL-60 leukemia cells. After signal or sham excitation, intracellular calcium level responses varied with activator concentration and with the activated state of the cells.",
  "effect_direction": "unclear",
  "limitations": [
    "No quantitative results or direction of effect reported in the abstract",
    "Exposure parameters are incompletely described (e.g., field strength, frequency in Hz, duration)",
    "Sample size not reported"
  ],
  "evidence_strength": "insufficient",
  "confidence": 0.62,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "extremely-low-frequency",
    "electromagnetic field",
    "electric field",
    "HL-60",
    "leukemia cells",
    "calcium flux",
    "Ca2+ transport",
    "ion channels",
    "intracellular calcium",
    "sham excitation"
  ],
  "suggested_hubs": []
}