A device for radiofrequency assisted hepatic resection.

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference · 2004 · Unclear · Insufficient evidence

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UnclearInsufficient evidencePaper 3627

The authors describe a prototype linear array of RF electrodes used in bipolar mode to heat tissue between electrodes to near 100°C, enabling coagulation of a 1–2 cm tissue plane including large vessels. They report results from ex vivo and in vivo experiment…

Study snapshot

PublicationConference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference · 2004
Study typeengineering
Reported directionUnclear
Evidence ratingInsufficient

Abstract

Hepatic resection is the current standard treatment for hepatic malignancies. During hepatic resection part of the liver containing the tumor is surgically removed. This type of surgery is associated with high blood loss of approximately 1 L. Blood loss is associated with increased complication rates, prolonged hospital stay and reduced patient survival, especially when transfusion is required. We present a device that allows coagulation of a plane of tissue 1 to 2 cm wide, including coagulation of large vessels. This enables reduction of blood loss to a minimum by performing surgery along the coagulated tissue plane. The device consists of a linear array of radiofrequency (RF) electrodes 1.5 cm apart. By application of RF current in bipolar mode between two adjacent electrodes, temperatures close to 100 degrees C are obtained in-between electrodes enabling coagulation of large vessels. Rapid switching of applied current between all adjacent electrode pairs enables rapid heating of a tissue slice. We present a prototype device including results from ex vivo and in vivo experiments.

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AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeengineering
Effect directionunclear
PopulationNot supplied
Sample sizeNot supplied
ExposureRF
Evidence strengthInsufficientConfidence: 66% · Peer reviewed: yes

Main findings

The authors describe a prototype linear array of RF electrodes used in bipolar mode to heat tissue between electrodes to near 100°C, enabling coagulation of a 1–2 cm tissue plane including large vessels. They report results from ex vivo and in vivo experiments with the prototype device.

Outcomes measured

  • Tissue coagulation (1–2 cm plane)
  • Ability to coagulate large vessels
  • Temperature achieved in tissue (~100°C)
  • Blood loss reduction during hepatic resection (intended/claimed)

Limitations

  • No frequency, power, or dosimetry parameters reported in the abstract
  • No quantitative results for blood loss reduction or experimental outcomes provided in the abstract
  • Ex vivo and in vivo experiments are mentioned but details (species/subjects, sample size, controls) are not provided
View raw extracted JSON
{
  "study_type": "engineering",
  "exposure": {
    "band": "RF",
    "source": "medical device (radiofrequency electrodes for hepatic resection)",
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": null
  },
  "population": null,
  "sample_size": null,
  "outcomes": [
    "Tissue coagulation (1–2 cm plane)",
    "Ability to coagulate large vessels",
    "Temperature achieved in tissue (~100°C)",
    "Blood loss reduction during hepatic resection (intended/claimed)"
  ],
  "main_findings": "The authors describe a prototype linear array of RF electrodes used in bipolar mode to heat tissue between electrodes to near 100°C, enabling coagulation of a 1–2 cm tissue plane including large vessels. They report results from ex vivo and in vivo experiments with the prototype device.",
  "effect_direction": "unclear",
  "limitations": [
    "No frequency, power, or dosimetry parameters reported in the abstract",
    "No quantitative results for blood loss reduction or experimental outcomes provided in the abstract",
    "Ex vivo and in vivo experiments are mentioned but details (species/subjects, sample size, controls) are not provided"
  ],
  "evidence_strength": "insufficient",
  "confidence": 0.66,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "hepatic resection",
    "radiofrequency",
    "RF electrodes",
    "bipolar mode",
    "coagulation",
    "blood loss",
    "surgical device",
    "ex vivo",
    "in vivo"
  ],
  "suggested_hubs": [
    {
      "slug": "engineering",
      "weight": 0.9,
      "reason": "Prototype RF electrode array device for surgical coagulation is the focus."
    }
  ]
}
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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1109/iembs.2004.1403721
PubMed: 17270781

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