RF Safe

A preclinical study of nonsurgical radiofrequency collagen remodeling for the treatment of stress urinary incontinence.

Expert review of medical devices · 2006 · Unclear · Insufficient evidence

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UnclearInsufficient evidencePaper 3520

Many women with stress urinary incontinence seek a nonsurgical, well-tolerated, effective and durable treatment that is associated with a rapid recovery and improvement in quality of life. However, the nonsurgical options available, such as pelvic floor exerc…

Study snapshot

PublicationExpert review of medical devices · 2006
Study typeanimal
Reported directionUnclear
Evidence ratingInsufficient

Abstract

Many women with stress urinary incontinence seek a nonsurgical, well-tolerated, effective and durable treatment that is associated with a rapid recovery and improvement in quality of life. However, the nonsurgical options available, such as pelvic floor exercises or behavioral therapy, are typically not effective; thus, many women with the condition remain untreated. A new nonsurgical treatment, transurethral radiofrequency collagen remodeling, offers many patient-desired treatment characteristics. This prospective, controlled animal study was performed to evaluate the safety, gross and histological impact, and physiological effect of transurethral radiofrequency collagen remodeling. The outcomes served as the basis for initial and subsequent clinical trials in women.

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeanimal
Effect directionunclear
PopulationAnimal model (species not specified)
Sample sizeNot supplied
ExposureRF
Evidence strengthInsufficientConfidence: 62% · Peer reviewed: yes

Main findings

Many women with stress urinary incontinence seek a nonsurgical, well-tolerated, effective and durable treatment that is associated with a rapid recovery and improvement in quality of life. However, the nonsurgical options available, such as pelvic floor exerc…

Outcomes measured

  • Safety
  • Gross impact
  • Histological impact
  • Physiological effect

Limitations

  • No quantitative results reported in the provided abstract
  • Animal species/model not specified
  • Radiofrequency exposure parameters (e.g., frequency, dose/SAR, duration) not provided
  • Sample size not provided
View raw extracted JSON
{
  "study_type": "animal",
  "exposure": {
    "band": "RF",
    "source": "transurethral radiofrequency collagen remodeling",
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": null
  },
  "population": "Animal model (species not specified)",
  "sample_size": null,
  "outcomes": [
    "Safety",
    "Gross impact",
    "Histological impact",
    "Physiological effect"
  ],
  "main_findings": null,
  "effect_direction": "unclear",
  "limitations": [
    "No quantitative results reported in the provided abstract",
    "Animal species/model not specified",
    "Radiofrequency exposure parameters (e.g., frequency, dose/SAR, duration) not provided",
    "Sample size not provided"
  ],
  "evidence_strength": "insufficient",
  "confidence": 0.62,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "stress urinary incontinence",
    "transurethral",
    "radiofrequency",
    "collagen remodeling",
    "nonsurgical treatment",
    "animal study",
    "safety",
    "histology",
    "physiological effect"
  ],
  "suggested_hubs": []
}
AI can be wrong. Always verify against the paper.

AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1586/17434440.3.6.743
PubMed: 17280538

Read the original paper →

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