The effect of electromagnetic radiation emitted by display screens on cell oxygen metabolism - in vitro studies.

Archives of medical science : AMS · 2015 · Harm · Low evidence

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HarmLow evidencePaper 2995

Human blood platelet suspensions exposed to 1 kHz EMR at 150 V/m and 220 V/m for 30 or 60 minutes showed increased ROS concentration; the largest increase was reported at 220 V/m for 60 min. MDA increased significantly after 30 min at 220 V/m, while antioxida…

Study snapshot

PublicationArchives of medical science : AMS · 2015

Study typein_vitro

Reported directionHarm

Evidence ratingLow

Abstract

INTRODUCTION: Research studies carried out for decades have not solved the problem of the effect of electromagnetic radiation of various frequency and strength on the human organism. Due to this fact, we decided to investigate the changes taking place in human blood platelets under the effect of electromagnetic radiation (EMR) emitted by LCD monitors. MATERIAL AND METHODS: The changes of selected parameters of oxygen metabolism were measured, i.e. reactive oxygen species concentration, enzymatic activity of antioxidant defence proteins - superoxide dismutase (SOD-1) and catalase (CAT) - and malondialdehyde concentration (MDA). A suspension of human blood platelets was exposed to electromagnetic radiation of 1 kHz frequency and 150 V/m and 220 V/m intensity for 30 and 60 min. The level of changes of the selected parameters of oxidative stress was determined after the exposure and compared to the control samples (not exposed). RESULTS: The measurements revealed an increase of the concentration of reactive oxygen species. The largest increase of ROS concentration vs. the control sample was observed after exposure to EMF of 220 V/m intensity for 60 min (from x = 54.64 to x = 72.92). The measurement of MDA concentration demonstrated a statistically significant increase after 30-min exposure to an EMF of 220 V/m intensity in relation to the initial values (from x = 3.18 to x = 4.41). The enzymatic activity of SOD-1 decreased after exposure (the most prominent change was observed after 60-min and 220 V/m intensity from x = 3556.41 to x = 1084.83). The most significant change in activity of catalase was observed after 60 min and 220 v/m exposure (from x = 6.28 to x = 4.15). CONCLUSIONS: The findings indicate that exposure to electromagnetic radiation of 1 kHz frequency and 150 V/m and 220 V/m intensity may cause adverse effects within blood platelets' oxygen metabolism and thus may lead to physiological dysfunction of the organism.

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AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typein_vitro

Effect directionharm

PopulationHuman blood platelets (suspension)

Sample sizeNot supplied

ExposureELF · 0.001 MHz · 30 and 60 min

Evidence strengthLowConfidence: 78% · Peer reviewed: yes

Main findings

Outcomes measured

Reactive oxygen species (ROS) concentration
Superoxide dismutase (SOD-1) activity
Catalase (CAT) activity
Malondialdehyde (MDA) concentration (lipid peroxidation/oxidative stress marker)

Limitations

In vitro platelet suspension model; findings may not translate directly to whole-organism effects
No sample size reported in abstract
Exposure described in terms of frequency and field intensity; other dosimetry details not provided in abstract

View raw extracted JSON

{
  "study_type": "in_vitro",
  "exposure": {
    "band": "ELF",
    "source": "display screens (LCD monitors)",
    "frequency_mhz": 0.001,
    "sar_wkg": null,
    "duration": "30 and 60 min"
  },
  "population": "Human blood platelets (suspension)",
  "sample_size": null,
  "outcomes": [
    "Reactive oxygen species (ROS) concentration",
    "Superoxide dismutase (SOD-1) activity",
    "Catalase (CAT) activity",
    "Malondialdehyde (MDA) concentration (lipid peroxidation/oxidative stress marker)"
  ],
  "main_findings": "Human blood platelet suspensions exposed to 1 kHz EMR at 150 V/m and 220 V/m for 30 or 60 minutes showed increased ROS concentration; the largest increase was reported at 220 V/m for 60 min. MDA increased significantly after 30 min at 220 V/m, while antioxidant enzyme activities decreased after exposure (SOD-1 and catalase decreases most prominent at 60 min and 220 V/m).",
  "effect_direction": "harm",
  "limitations": [
    "In vitro platelet suspension model; findings may not translate directly to whole-organism effects",
    "No sample size reported in abstract",
    "Exposure described in terms of frequency and field intensity; other dosimetry details not provided in abstract"
  ],
  "evidence_strength": "low",
  "confidence": 0.78,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "electromagnetic radiation",
    "ELF",
    "1 kHz",
    "LCD monitors",
    "platelets",
    "oxidative stress",
    "reactive oxygen species",
    "SOD-1",
    "catalase",
    "malondialdehyde"
  ],
  "suggested_hubs": [
    {
      "slug": "el f-oxidative-stress",
      "weight": 0.6,
      "reason": "In vitro ELF (1 kHz) exposure with oxidative stress endpoints (ROS, MDA, antioxidant enzymes)."
    },
    {
      "slug": "consumer-electronics",
      "weight": 0.35,
      "reason": "Exposure source described as EMR emitted by LCD display screens/monitors."
    }
  ]
}

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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.5114/aoms.2015.56362
PubMed: 26788099

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