Impact of expectancy on fatigue by exposure to the fifth generation of mobile communication signals

Electromagnetic Biology and Medicine · 2025 · Mixed · Low evidence

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MixedLow evidencePaper 2666

In statistical comparisons, routine-level 5G RF-EMF exposure did not lead to changes in EEG power. Reported fatigue was influenced by the information given to participants about exposure order (correct/false/no information), including when there was no actual…

Study snapshot

PublicationElectromagnetic Biology and Medicine · 2025
Study typerandomized_trial
Reported directionMixed
Evidence ratingLow

Abstract

Category: Epidemiology Tags: RF-EMF, 5G signals, fatigue, expectancy, psychological priming, EEG, mobile communication health effects DOI: 10.1080/15368378.2025.2496151 URL: pubmed.ncbi.nlm.nih.gov Overview There is a long-standing debate about the relationship between Radio Frequency Electromagnetic Field (RF-EMF) exposure and fatigue. Past studies primarily rely on self-report scales to assess fatigue, but these methods are often susceptible to personal biases. Notably, the role of psychological factors in the fatigue response induced by RF-EMF exposure remains unclear. Study Design - 21 healthy subjects participated in three sessions. - Each session included two 30-min exposures to either real or sham 5G signals, with the order randomized. - Subjects were provided with correct, false, or no information about the order of exposure (informational conditions). Measurements - Fatigue scoring questionnaire - Electroencephalogram (EEG) measurements Findings - Statistical comparison indicates that 5G RF-EMF exposure at routine levels does not lead to changes in EEG power. - The report of fatigue can be altered by the conveyed information of being exposed to 5G signals, even when there is no actual exposure and no detectable electrophysiological indicator. Conclusion Our findings suggest that psychological priming can influence reported fatigue in studies of RF-EMF exposure. It is necessary to prevent or account for psychological priming to accurately reveal the effects of RF-EMF exposure.

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AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typerandomized_trial
Effect directionmixed
Population21 healthy subjects
Sample size21
ExposureRF · Two 30-min exposures per session; three sessions
Evidence strengthLowConfidence: 78% · Peer reviewed: yes

Main findings

In statistical comparisons, routine-level 5G RF-EMF exposure did not lead to changes in EEG power. Reported fatigue was influenced by the information given to participants about exposure order (correct/false/no information), including when there was no actual exposure and no detectable electrophysiological indicator.

Outcomes measured

  • Fatigue (questionnaire)
  • EEG power

Limitations

  • Small sample size (21 subjects)
  • Fatigue outcome relies on self-report questionnaire
  • Exposure parameters (e.g., frequency, SAR) not specified in the provided abstract
  • Short exposure duration (30 minutes per exposure)
View raw extracted JSON
{
  "publication_year": 2025,
  "study_type": "randomized_trial",
  "exposure": {
    "band": "RF",
    "source": "5G mobile communication signals",
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": "Two 30-min exposures per session; three sessions"
  },
  "population": "21 healthy subjects",
  "sample_size": 21,
  "outcomes": [
    "Fatigue (questionnaire)",
    "EEG power"
  ],
  "main_findings": "In statistical comparisons, routine-level 5G RF-EMF exposure did not lead to changes in EEG power. Reported fatigue was influenced by the information given to participants about exposure order (correct/false/no information), including when there was no actual exposure and no detectable electrophysiological indicator.",
  "effect_direction": "mixed",
  "limitations": [
    "Small sample size (21 subjects)",
    "Fatigue outcome relies on self-report questionnaire",
    "Exposure parameters (e.g., frequency, SAR) not specified in the provided abstract",
    "Short exposure duration (30 minutes per exposure)"
  ],
  "evidence_strength": "low",
  "confidence": 0.78,
  "peer_reviewed_likely": "yes",
  "stance": "neutral",
  "stance_confidence": 0.74,
  "summary": "This randomized sham-controlled study in 21 healthy participants tested whether routine-level 5G RF-EMF exposure affects fatigue and EEG power, while manipulating expectancy via correct, false, or no information about exposure order. The study reports no change in EEG power with real versus sham exposure. However, self-reported fatigue varied with the conveyed information about being exposed, suggesting an expectancy/psychological priming effect on symptom reporting.",
  "key_points": [
    "Participants completed three sessions with randomized real and sham 5G exposures.",
    "Each session included two 30-minute exposure periods.",
    "Expectancy was manipulated by providing correct, false, or no information about exposure order.",
    "Routine-level 5G exposure was reported not to change EEG power.",
    "Self-reported fatigue was influenced by the information given about exposure, even without actual exposure.",
    "Authors conclude psychological priming should be prevented or accounted for in RF-EMF fatigue research."
  ],
  "categories": [
    "RF-EMF",
    "5G",
    "Epidemiology",
    "Symptoms",
    "Neurophysiology"
  ],
  "tags": [
    "5G Signals",
    "RF-EMF Exposure",
    "Fatigue",
    "Expectancy Effects",
    "Psychological Priming",
    "Sham Exposure",
    "Randomized Order",
    "EEG Power",
    "Nocebo Effect",
    "Symptom Reporting"
  ],
  "keywords": [
    "RF-EMF",
    "5G signals",
    "fatigue",
    "expectancy",
    "psychological priming",
    "EEG",
    "mobile communication health effects"
  ],
  "suggested_hubs": [
    {
      "slug": "5g-policy",
      "weight": 0.62,
      "reason": "Study directly examines effects and expectancy related to 5G signal exposure."
    }
  ],
  "social": {
    "tweet": "Randomized sham-controlled study (n=21) found routine-level 5G RF-EMF did not change EEG power, but reported fatigue shifted with the information participants received about being exposed—highlighting expectancy/priming effects.",
    "facebook": "In a small randomized sham-controlled experiment, routine-level 5G RF-EMF exposure was not associated with changes in EEG power. Reported fatigue, however, was influenced by what participants were told about exposure, suggesting expectancy can shape symptom reports.",
    "linkedin": "A randomized sham-controlled study in 21 healthy participants reports no EEG power changes with routine-level 5G RF-EMF exposure, while self-reported fatigue was modulated by conveyed information about exposure order—underscoring the role of expectancy/psychological priming in symptom reporting."
  }
}
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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1080/15368378.2025.2496151
PubMed: 40269539

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