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Residential magnetic fields exposure and childhood leukemia: a population-based case-control study in California

2017 · Harm · Moderate evidence

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HarmModerate evidencePaper 2106

The study found an association between residential magnetic field exposure and childhood leukemia, with an odds ratio of 2.19 (95% CI 1.12-4.31) in the highest exposure category (>0.125 µT). Wiring-based models were more predictive of long-term exposure than …

Study snapshot

Publicationmanual · 2017
Study typecase_control
Reported directionHarm
Evidence ratingModerate

Abstract

- Extremely Low Frequency Fields Residential magnetic fields exposure and childhood leukemia: a population-based case-control study in California Thomas DC. Re: Kheifets et al. (2017): Residential magnetic fields exposure and childhood leukemia: a population-based case-control study in California. Cancer Causes Control 2018. doi:10.1007/s10552-018-1037-9 No abstract Excerpts In contrast, our LA County study reported OR 2.19 (95% CI 1.12-4.31; p for trend = .007) in our highest exposure category (MF > 0.125 µT) ..., Finally, our wiring-based model found an association between residential MF and childhood leukemia when measurements alone did not [2], supporting the hypothesis that the temporal stability of distribution and transmission lines makes their wiring characteristics a better predictor of long-term residential MF exposures. Discussion of possible mechanisms that could account for our reported effects as lower levels is beyond the scope of this comparison with previous literature, but a brief summary is provided in the Supplementary Comments. These findings suggest that innovations in ELF-MF exposure assessment may lead to more informative studies of the childhood leukemia association than the HVTL-only approach. link.springer.com

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typecase_control
Effect directionharm
Populationchildren in California
Sample sizeNot supplied
ExposureELF
Evidence strengthModerateConfidence: 70% · Peer reviewed: yes

Main findings

The study found an association between residential magnetic field exposure and childhood leukemia, with an odds ratio of 2.19 (95% CI 1.12-4.31) in the highest exposure category (>0.125 µT). Wiring-based models were more predictive of long-term exposure than measurements alone.

Outcomes measured

  • childhood leukemia

Limitations

  • No abstract provided, limiting detailed extraction
  • Sample size not specified
  • Details on exposure duration and frequency not provided
View raw extracted JSON
{
  "study_type": "case_control",
  "exposure": {
    "band": "ELF",
    "source": "residential magnetic fields",
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": null
  },
  "population": "children in California",
  "sample_size": null,
  "outcomes": [
    "childhood leukemia"
  ],
  "main_findings": "The study found an association between residential magnetic field exposure and childhood leukemia, with an odds ratio of 2.19 (95% CI 1.12-4.31) in the highest exposure category (>0.125 µT). Wiring-based models were more predictive of long-term exposure than measurements alone.",
  "effect_direction": "harm",
  "limitations": [
    "No abstract provided, limiting detailed extraction",
    "Sample size not specified",
    "Details on exposure duration and frequency not provided"
  ],
  "evidence_strength": "moderate",
  "confidence": 0.7,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "ELF",
    "magnetic fields",
    "childhood leukemia",
    "residential exposure",
    "case-control study"
  ],
  "suggested_hubs": [
    {
      "slug": "occupational-exposure",
      "weight": 0.3,
      "reason": "Study of residential magnetic field exposure relevant to exposure assessment"
    },
    {
      "slug": "who-icnirp",
      "weight": 0.7,
      "reason": "Study relates to ELF magnetic fields and health outcomes relevant to guidelines"
    }
  ]
}
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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1007/s10552-018-1037-9
PubMed: Not supplied

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