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Effects of mobile phone prolonged radiation on kidney cells; an in-vitro study

2018 · Harm · Low evidence

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HarmLow evidencePaper 1988

Radiation exposure from a mobile phone simulator decreased kidney cell survival in exposed groups (reported up to 40%). A significant decrease in cell survival was observed in exposed groups versus control (P = 0.014), with no significant difference between t…

Study snapshot

Publicationmanual · 2018
Study typein_vitro
Reported directionHarm
Evidence ratingLow

Abstract

Effects of mobile phone prolonged radiation on kidney cells; an in-vitro study Mahmoudi, G, Nikzad, S, Mehrpouyan, M, Moslehi, M, Baradaran-Ghahfarokhi, M, Dashty, A. Effects of mobile phone prolonged radiation on kidney cells; an in-vitro study. J Renal Injury Prevention. 7(3):175-179.DOI: 10.15171/jrip.2018.42. Published Sep, 2018. Abstract Introduction: Mobile phones have been shown to have hazardous effects on the human renal system, reproduction and development, central nervous system and immune function. Objectives: This study aimed to investigate whether the mobile phone prolonged radiofrequency (RF) radiation could affect healthy kidney cells in an in-vitro study. Materials and Methods: Human kidney healthy cells in three groups were placed into three batches. The first and second groups (exposed groups) were exposed to a mobile phone simulator for 1 and 2 h/d, respectively. The irradiation was performed for 8 consecutive days. For the third group (control group), no radiation was applied to the samples and they completed the assay cycle under identical conditions. Cells' survival was evaluated using MTT [3-(4,5-dimethylthiazol-2yl)-2,5-diphenyltetrazolium bromide] assay. Statistical significance of the differences between control and exposed groups were assessed using the repeated measure ANOVA method (P < 0.05). Results: Results showed that radiation exposure from mobile phones simulator decreased the kidney cell survival in the exposed groups (up to 40%). ANOVA test revealed that a significant decrease in cell survival in the exposed group compared to the control group (P = 0.014). No significant differences between the irradiated groups were found (P > 0.05). Conclusion: Mobile phone exposure affects kidney cells survival during an in vitro condition. To study the effects of mobile phone radiation on kidney, further in vivo studies on mammalians are needed. journalrip.com

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typein_vitro
Effect directionharm
PopulationHuman healthy kidney cells (in vitro)
Sample sizeNot supplied
ExposureRF · 1 or 2 h/day for 8 consecutive days
Evidence strengthLowConfidence: 78% · Peer reviewed: yes

Main findings

Radiation exposure from a mobile phone simulator decreased kidney cell survival in exposed groups (reported up to 40%). A significant decrease in cell survival was observed in exposed groups versus control (P = 0.014), with no significant difference between the 1 h/day and 2 h/day exposure groups (P > 0.05).

Outcomes measured

  • Cell survival (MTT assay)

Limitations

  • In vitro study (not in vivo)
  • Exposure parameters such as frequency and SAR not reported in the abstract
  • Sample size not reported in the abstract
View raw extracted JSON
{
  "study_type": "in_vitro",
  "exposure": {
    "band": "RF",
    "source": "mobile phone simulator",
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": "1 or 2 h/day for 8 consecutive days"
  },
  "population": "Human healthy kidney cells (in vitro)",
  "sample_size": null,
  "outcomes": [
    "Cell survival (MTT assay)"
  ],
  "main_findings": "Radiation exposure from a mobile phone simulator decreased kidney cell survival in exposed groups (reported up to 40%). A significant decrease in cell survival was observed in exposed groups versus control (P = 0.014), with no significant difference between the 1 h/day and 2 h/day exposure groups (P > 0.05).",
  "effect_direction": "harm",
  "limitations": [
    "In vitro study (not in vivo)",
    "Exposure parameters such as frequency and SAR not reported in the abstract",
    "Sample size not reported in the abstract"
  ],
  "evidence_strength": "low",
  "confidence": 0.78,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "mobile phone",
    "radiofrequency",
    "RF radiation",
    "kidney cells",
    "cell survival",
    "MTT assay",
    "in vitro"
  ],
  "suggested_hubs": []
}
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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.15171/jrip.2018.42
PubMed: Not supplied

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