RF Safe

Radio frequency-induced superoxide accumulation affected the growth and viability of Saccharomyces cerevisiae (baker's yeast)

2020 · Mixed · Low evidence

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MixedLow evidencePaper 1619

Yeast growth and viability changed in a time-dependent manner under RF-EMF exposure (2.6–5 MHz) at very low power density reported as below 0.1 mT. Growth increased by 43.5% at 30 h but decreased (growth inhibition) by 20.7% at 89 h; viability increased to 70…

Study snapshot

Publicationmanual · 2020
Study typein_vitro
Reported directionMixed
Evidence ratingLow

Abstract

Radio frequency-induced superoxide accumulation affected the growth and viability of Saccharomyces cerevisiae (baker's yeast) Li Q, Tian M, Teng J, Gao P, Tang BQ, Wu H. Radio frequency-induced superoxide accumulation affected the growth and viability of Saccharomyces cerevisiae. Int Microbiol. 2020 Jan 2. doi: 10.1007/s10123-019-00111-2. Abstract With the development of the electric technologies, the biological effects of electromagnetic fields (EMF) were widely studied. However, the results remain controversial and the biophysical mechanisms are still unknown. To our knowledge, little studies pay attention to the radio frequency (RF) of 2.6-5 MHz. In the present study, we investigated the effect of these radio frequencies on the growth and cell viability of Saccharomyces cerevisiae at very low power density below 0.1 mT. The result appeared to be time-dependent. The growth of the yeast cells was obviously affected by the RF-EMF with a 43.5% increase when exposed for 30 h, and the growth-promoting effect decreased along with the radiation time and eventually turned to an inhibiting effect retarding growth by 20.7% at 89 h. The cell viability was improved to 70.1% at 8 h and reduced by 33.5% at 28 h. The superoxide accumulated in exposed cells as radiation time increased which may lead to the inhibition of viability and growth of the cells. However, the efficient frequency, power density, and exposure dosage await further investigation. Nevertheless, the wave band studied in this research is effective to produce biological effect, and therefore, it may provide an optional new radio frequency which is valuable for the development and utilization in therapy technique and medical use. ncbi.nlm.nih.gov

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typein_vitro
Effect directionmixed
PopulationSaccharomyces cerevisiae (baker's yeast) cells
Sample sizeNot supplied
ExposureRF · 8–89 h (time-dependent effects reported; specific endpoints at 8 h, 28 h, 30 h, 89 h)
Evidence strengthLowConfidence: 74% · Peer reviewed: yes

Main findings

Yeast growth and viability changed in a time-dependent manner under RF-EMF exposure (2.6–5 MHz) at very low power density reported as below 0.1 mT. Growth increased by 43.5% at 30 h but decreased (growth inhibition) by 20.7% at 89 h; viability increased to 70.1% at 8 h but was reduced by 33.5% at 28 h. Superoxide accumulated in exposed cells as radiation time increased.

Outcomes measured

  • Yeast growth
  • Cell viability
  • Superoxide accumulation

Limitations

  • Mechanisms described as unknown/controversial in the field
  • Efficient frequency, power density, and exposure dosage stated to require further investigation
  • Exposure metric described as 'power density below 0.1 mT' (units/characterization unclear in abstract)
  • Sample size and detailed methods not provided in abstract
View raw extracted JSON
{
  "study_type": "in_vitro",
  "exposure": {
    "band": "RF",
    "source": null,
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": "8–89 h (time-dependent effects reported; specific endpoints at 8 h, 28 h, 30 h, 89 h)"
  },
  "population": "Saccharomyces cerevisiae (baker's yeast) cells",
  "sample_size": null,
  "outcomes": [
    "Yeast growth",
    "Cell viability",
    "Superoxide accumulation"
  ],
  "main_findings": "Yeast growth and viability changed in a time-dependent manner under RF-EMF exposure (2.6–5 MHz) at very low power density reported as below 0.1 mT. Growth increased by 43.5% at 30 h but decreased (growth inhibition) by 20.7% at 89 h; viability increased to 70.1% at 8 h but was reduced by 33.5% at 28 h. Superoxide accumulated in exposed cells as radiation time increased.",
  "effect_direction": "mixed",
  "limitations": [
    "Mechanisms described as unknown/controversial in the field",
    "Efficient frequency, power density, and exposure dosage stated to require further investigation",
    "Exposure metric described as 'power density below 0.1 mT' (units/characterization unclear in abstract)",
    "Sample size and detailed methods not provided in abstract"
  ],
  "evidence_strength": "low",
  "confidence": 0.74,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "radio frequency",
    "RF-EMF",
    "2.6–5 MHz",
    "Saccharomyces cerevisiae",
    "yeast",
    "growth",
    "cell viability",
    "superoxide",
    "oxidative stress",
    "time-dependent effects"
  ],
  "suggested_hubs": []
}
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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1007/s10123-019-00111-2
PubMed: Not supplied

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