Assessment of the Cellphone Radiation Effects on Anti-oxidative and Renal Parameters in Rat

2019 · Mixed · Low evidence

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MixedLow evidencePaper 1577

Compared with controls, catalase, SOD, and paraoxonase activities were significantly increased in exposed groups at 15 and 30 days, while glutathione peroxidase activity was decreased. MDA and creatinine showed no significant changes; urea and uric acid were …

Study snapshot

Publicationmanual · 2019

Study typeanimal

Reported directionMixed

Evidence ratingLow

Abstract

Assessment of the Cellphone Radiation Effects on Anti-oxidative and Renal Parameters in Rat Eslami E, Fatahian S, Shahanipour K. Assessment of the Cellphone Radiations Effects on Anti-oxidative and Renal Parameters in Rat. Toxicology and Environmental Health Sciences. 11(4):278-282. Dec 2019. Objective: In the present study an attempt is to assess the cellphones waves effects on the stress oxidative activities as well as renal parameters in rat. Methods: 30 mature male Wister rats were divided into 3 groups of 10. Group 1 (control) was kept in normal laboratory conditions. Groups 2 and 3 were exposed with two and four cellphones in opposite sides of the cage, respectively. Blood samples were collected directly from the rat's heart 15 and 30 days post exposure and the activity of anti-oxidative factors including Glutathione Peroxidase, Superoxide Dismutase, Catalase, Glutathione Peroxidase, Paraoxonase and Malondialdehyde as well as renal parameters (Urea, Uric acid and Creatinine) were measured. Results: Activity of catalase, superoxide dismutase and paraoxonase enzymes in all treated groups, 15 and 30 days post cellphone exposure were significantly increased in comparison with control. The activity of glutathione peroxidase enzyme in all treated groups, 15 and 30 days post cellphone exposure was decreased in comparison with control. Malondialdehyde and creatinine activity did not show any significant changes. Uric acid and urea were significantly increased in the group just exposed with four cellphones, 30 days post exposure. Conclusion: According to the results, many changes were seen in biochemical parameters due to the cellphone exposure during a month. Therefore it can be concluded that radio frequency devices could be destructive and have many negative effects on the tissues and enzyme function. link.springer.com

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AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeanimal

Effect directionmixed

Population30 mature male Wister rats

Sample size30

ExposureRF · 15 and 30 days post exposure (exposure duration not otherwise specified)

Evidence strengthLowConfidence: 78% · Peer reviewed: yes

Main findings

Outcomes measured

Catalase activity
Superoxide dismutase (SOD) activity
Paraoxonase activity
Glutathione peroxidase activity
Malondialdehyde (MDA)
Urea
Uric acid
Creatinine

Limitations

Frequency and SAR/exposure level not reported
Exposure protocol details (e.g., call mode/standby, distance to animals, daily exposure duration) not described in the abstract
Only male rats studied
Short follow-up (up to 30 days)

View raw extracted JSON

{
  "study_type": "animal",
  "exposure": {
    "band": "RF",
    "source": "mobile phone",
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": "15 and 30 days post exposure (exposure duration not otherwise specified)"
  },
  "population": "30 mature male Wister rats",
  "sample_size": 30,
  "outcomes": [
    "Catalase activity",
    "Superoxide dismutase (SOD) activity",
    "Paraoxonase activity",
    "Glutathione peroxidase activity",
    "Malondialdehyde (MDA)",
    "Urea",
    "Uric acid",
    "Creatinine"
  ],
  "main_findings": "Compared with controls, catalase, SOD, and paraoxonase activities were significantly increased in exposed groups at 15 and 30 days, while glutathione peroxidase activity was decreased. MDA and creatinine showed no significant changes; urea and uric acid were significantly increased only in the group exposed to four cellphones at 30 days.",
  "effect_direction": "mixed",
  "limitations": [
    "Frequency and SAR/exposure level not reported",
    "Exposure protocol details (e.g., call mode/standby, distance to animals, daily exposure duration) not described in the abstract",
    "Only male rats studied",
    "Short follow-up (up to 30 days)"
  ],
  "evidence_strength": "low",
  "confidence": 0.78,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "cellphone radiation",
    "radiofrequency",
    "oxidative stress",
    "antioxidant enzymes",
    "renal parameters",
    "rat",
    "catalase",
    "superoxide dismutase",
    "glutathione peroxidase",
    "paraoxonase",
    "urea",
    "uric acid",
    "creatinine"
  ],
  "suggested_hubs": []
}

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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1007/s13530-019-0414-4
PubMed: Not supplied

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