Environmental Pollution, Oxidative Stress and Thioretinaco Ozonide: Effects of Glyphosate, Fluoride and Electromagnetic Fields on Mitochondrial Dysfunction in Carcinogenesis, Atherogenesis and Aging

2020 · Harm · Insufficient evidence

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HarmInsufficient evidencePaper 1461

Study snapshot

Publicationmanual · 2020

Study typereview

Reported directionHarm

Evidence ratingInsufficient

Abstract

Environmental Pollution, Oxidative Stress and Thioretinaco Ozonide: Effects of Glyphosate, Fluoride and Electromagnetic Fields on Mitochondrial Dysfunction in Carcinogenesis, Atherogenesis and Aging Kilmer S. McCully. Environmental Pollution, Oxidative Stress and Thioretinaco Ozonide: Effects of Glyphosate, Fluoride and Electromagnetic Fields on Mitochondrial Dysfunction in Carcinogenesis, Atherogenesis and Aging. Annals of Clinical and Laboratory Science. 50(3):408-411. May-June 2020. Abstract Environmental pollutants, such as pesticides, herbicides, additives to food and water, and electromagnetic fields threaten public health by promotion of cancer, heart disease and chronic diseases of aging. Many of these pollutants cause adverse health outcomes by effects on mitochondrial function to produce oxidative stress through loss of the active site complex for oxidative phosphorylation, thioretinaco ozonide oxygen nicotinamide adenine dinucleotide phosphate, from opening of the mitochondrial permeability transition pore. Glyphosate, fluoride, and electromagnetic fields are examples of carcinogenic pollutants that promote loss and decomposition of the active site for oxidative phosphorylation, producing mitochondrial dysfunction and oxidative stress. Ionizing radiation has long been known to be carcinogenic, and non-ionizing electromagnetic fields from microwaves, radar, cell phones and cathode ray screens are carcinogenic and produce deleterious effects on capillaries, nerve cells, blood brain barrier, embryonic and germ cells, lenses and cardiac function. Adverse health effects of electromagnetic fields include cataracts, infertility, congenital malformations, cancer, lymphocytosis, leukemia, hearing loss, blindness, retinal hemorrhages, cardiac arrhythmias, dermatitis, hair loss, depression, memory loss, premature aging, heart attacks, and weaponized mind control. The hyperhomocysteinemia, suppressed immunity, and altered oxidative metabolism observed in atherosclerosis and dementia are attributed to deficiency of adenosyl methionine which results from increased polyamine biosynthesis by pathogenic microbes that are demonstrated in atherosclerotic plaques and cerebral plaques. Thus, environmental pollutants potentially promote diseases of aging, atherosclerosis, cancer, and premature aging by production of mitochondrial dysfunction. annclinlabsci.org

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AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typereview

Effect directionharm

PopulationNot supplied

Sample sizeNot supplied

ExposureNot supplied

Evidence strengthInsufficientConfidence: 74% · Peer reviewed: unknown

Main findings

The article asserts that environmental pollutants including non-ionizing electromagnetic fields promote mitochondrial dysfunction and oxidative stress, contributing to cancer, atherosclerosis/heart disease, and diseases of aging. It further claims non-ionizing electromagnetic fields from sources such as microwaves, radar, cell phones, and cathode ray screens are carcinogenic and associated with a wide range of adverse health effects.

Outcomes measured

mitochondrial dysfunction
oxidative stress
carcinogenesis/cancer
atherogenesis/heart disease
aging/premature aging
cataracts
infertility
congenital malformations
lymphocytosis
leukemia
hearing loss
blindness
retinal hemorrhages
cardiac arrhythmias
dermatitis
hair loss
depression
memory loss
heart attacks

Limitations

Narrative assertions without described study design, methods, or quantitative results in the abstract
No exposure metrics (frequency, intensity, SAR) or duration provided for electromagnetic fields
No population, sample size, or statistical analysis described
Broad range of outcomes listed without specifying evidence sources or strength

View raw extracted JSON

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  "study_type": "review",
  "exposure": {
    "band": null,
    "source": "microwaves, radar, cell phones, cathode ray screens",
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": null
  },
  "population": null,
  "sample_size": null,
  "outcomes": [
    "mitochondrial dysfunction",
    "oxidative stress",
    "carcinogenesis/cancer",
    "atherogenesis/heart disease",
    "aging/premature aging",
    "cataracts",
    "infertility",
    "congenital malformations",
    "lymphocytosis",
    "leukemia",
    "hearing loss",
    "blindness",
    "retinal hemorrhages",
    "cardiac arrhythmias",
    "dermatitis",
    "hair loss",
    "depression",
    "memory loss",
    "heart attacks"
  ],
  "main_findings": "The article asserts that environmental pollutants including non-ionizing electromagnetic fields promote mitochondrial dysfunction and oxidative stress, contributing to cancer, atherosclerosis/heart disease, and diseases of aging. It further claims non-ionizing electromagnetic fields from sources such as microwaves, radar, cell phones, and cathode ray screens are carcinogenic and associated with a wide range of adverse health effects.",
  "effect_direction": "harm",
  "limitations": [
    "Narrative assertions without described study design, methods, or quantitative results in the abstract",
    "No exposure metrics (frequency, intensity, SAR) or duration provided for electromagnetic fields",
    "No population, sample size, or statistical analysis described",
    "Broad range of outcomes listed without specifying evidence sources or strength"
  ],
  "evidence_strength": "insufficient",
  "confidence": 0.74,
  "peer_reviewed_likely": "unknown",
  "keywords": [
    "electromagnetic fields",
    "non-ionizing radiation",
    "microwaves",
    "radar",
    "cell phones",
    "cathode ray screens",
    "mitochondrial dysfunction",
    "oxidative stress",
    "thioretinaco ozonide",
    "mitochondrial permeability transition pore",
    "carcinogenesis",
    "atherogenesis",
    "aging"
  ],
  "suggested_hubs": [
    {
      "slug": "who-icnirp",
      "weight": 0.25,
      "reason": "Discusses carcinogenicity and health effects of non-ionizing electromagnetic fields, relevant to major guideline/policy discussions."
    }
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}

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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: Not supplied
PubMed: Not supplied

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