Review paper: Proteomic impacts of electromagnetic fields on the male reproductive system

2016 · Harm · Insufficient evidence

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HarmInsufficient evidencePaper 1445

The review describes experimental and clinical evidence reporting associations between regular mobile phone use or EMF exposure and reduced sperm quantity/quality, along with biomarkers and pathological, endocrine, and proteomic changes in sperm. The authors …

Study snapshot

Publicationmanual · 2016
Study typereview
Reported directionHarm
Evidence ratingInsufficient

Abstract

Review paper: Proteomic impacts of electromagnetic fields on the male reproductive system Sepehrimanesh, M. & Davis, D.L. Proteomic impacts of electromagnetic fields on the male reproductive system. Comp Clin Pathol (2016). doi:10.1007/s00580-016-2342-x Published online Oct 13, 2016. Abstract The use of mobile phones and other wireless transmitting devices is increasing dramatically in developing and developed countries, as is the rate of infertility. A number of respected infertility clinics in Australia, India, USA, and Iran are reporting that those who regularly use mobile phones tend to have reduced sperm quantity and quality. Some experimental studies have found that human sperm exposed to electromagnetic fields (EMF), either simulated or from mobile phones, developed biomarkers of impaired structure and function, as well as reduced quantity. These encompass pathological, endocrine, and proteomic changes. Proteins perform a vast array of functions within living organisms, and the proteome is the entire array of proteins-the ultimate biomolecules in the pathways of DNA transcription to translation. Proteomics is the art and science of studying all proteins in cells, using different techniques. This paper reviews proteomic experimental and clinical evidence that EMF acts as a male-mediated teratogen and contributor to infertility. link.springer.com Not yet archived in PubMed. Also see: saferemr.com

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typereview
Effect directionharm
PopulationMale reproductive system / human sperm (experimental and clinical evidence discussed)
Sample sizeNot supplied
ExposureRF
Evidence strengthInsufficientConfidence: 66% · Peer reviewed: yes

Main findings

The review describes experimental and clinical evidence reporting associations between regular mobile phone use or EMF exposure and reduced sperm quantity/quality, along with biomarkers and pathological, endocrine, and proteomic changes in sperm. The authors conclude that EMF acts as a male-mediated teratogen and contributor to infertility.

Outcomes measured

  • sperm quantity
  • sperm quality
  • biomarkers of impaired sperm structure and function
  • pathological changes
  • endocrine changes
  • proteomic changes
  • male-mediated teratogenicity
  • infertility

Limitations

  • No specific frequencies, SAR levels, exposure durations, or quantitative effect sizes are provided in the abstract.
  • As a review, findings depend on the quality and heterogeneity of included experimental and clinical studies; inclusion criteria are not described in the abstract.
  • Sample sizes and study designs of the underlying evidence are not reported in the abstract.
View raw extracted JSON
{
  "study_type": "review",
  "exposure": {
    "band": "RF",
    "source": "mobile phone",
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": null
  },
  "population": "Male reproductive system / human sperm (experimental and clinical evidence discussed)",
  "sample_size": null,
  "outcomes": [
    "sperm quantity",
    "sperm quality",
    "biomarkers of impaired sperm structure and function",
    "pathological changes",
    "endocrine changes",
    "proteomic changes",
    "male-mediated teratogenicity",
    "infertility"
  ],
  "main_findings": "The review describes experimental and clinical evidence reporting associations between regular mobile phone use or EMF exposure and reduced sperm quantity/quality, along with biomarkers and pathological, endocrine, and proteomic changes in sperm. The authors conclude that EMF acts as a male-mediated teratogen and contributor to infertility.",
  "effect_direction": "harm",
  "limitations": [
    "No specific frequencies, SAR levels, exposure durations, or quantitative effect sizes are provided in the abstract.",
    "As a review, findings depend on the quality and heterogeneity of included experimental and clinical studies; inclusion criteria are not described in the abstract.",
    "Sample sizes and study designs of the underlying evidence are not reported in the abstract."
  ],
  "evidence_strength": "insufficient",
  "confidence": 0.66,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "electromagnetic fields",
    "EMF",
    "radiofrequency",
    "mobile phones",
    "wireless devices",
    "male reproductive system",
    "sperm",
    "infertility",
    "proteomics",
    "endocrine changes",
    "teratogen"
  ],
  "suggested_hubs": [
    {
      "slug": "rf-mobile-phones",
      "weight": 0.9,
      "reason": "Focuses on mobile phones/wireless transmitting devices and male fertility outcomes."
    }
  ]
}
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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1007/s00580-016-2342-x
PubMed: Not supplied

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