The Adverse Effect of Mobile Phone Radiations on Dorsal Root Ganglion of Albino Rats

2021 · Harm · Low evidence

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HarmLow evidencePaper 1169

Compared with controls, exposed rats showed histological changes in dorsal root ganglia including reduced cell size, cytoplasmic condensation, peripherally located heterochromatin nucleus, loss of nucleolus, and densely packed myelinated nerve fibers. The abs…

Study snapshot

Publicationmanual · 2021

Study typeanimal

Reported directionHarm

Evidence ratingLow

Abstract

The Adverse Effect of Mobile Phone Radiations on Dorsal Root Ganglion of Albino Rats Faisal Taufiq, Mohammed Bhilal Babu, Aqeel Ahmad, Mohammed Eajaz, Ahmed Shariff, Noureldaim Elnoman Elbadawi, Semmal Syed Meerasa. The Adverse Effect of Mobile Phone Radiations on Dorsal Root Ganglion of Albino Rats. Journal of Pharmaceutical Research International, 19 March 2021. Pages 54-60. DOI: 10.9734/jpri/2021/v33i1331266. Abstract Objectives: To assess the effect of Mobile Phone Radio Frequency Electromagnetic Radiation (RF-EMR) on the histological structure of dorsal root ganglia in albino rats. Methods: Twenty-four albino rats divided into one control and three experimental groups were studied for four weeks. The experimental groups were exposed to three different levels of RF-EMR through complete missed calls of 80,120 and160 calls per day respectively, using a GSM mobile phone of 0.9 GHz to1.8 GHz in silent mode. The dorsal root ganglia of the sacrificed Rats were examined under light and transmission electron microscope (TEM). Results: Dorsal root ganglions of exposed rats showed considerable histological changes like reduction in cell size, condensation of cytoplasm, peripherally located heterochromatin nucleus, loss of nucleolus and densely packed myelinated nerve fibers. No such changes were observed in control rats. Conclusion: Dorsal root ganglionic cells showed enduring and continuous changes when exposed to RF-EMR. The severity of histomorphological changes was dose-dependent, which increased constantly with radiation dosage increment. It might be fair to conclude that degenerative changes in the Dorsal Root Ganglion of the spinal cord, could be attributed to the long-term exposure to RF-EMR. Open access paper: journaljpri.com

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AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeanimal

Effect directionharm

PopulationAlbino rats

Sample size24

ExposureRF · 4 weeks

Evidence strengthLowConfidence: 78% · Peer reviewed: unknown

Main findings

Outcomes measured

Histological structure changes in dorsal root ganglia (light microscopy, TEM)

Limitations

Exposure quantified as number of missed calls/day rather than measured RF-EMR dose (e.g., SAR or field strength)
Frequency reported as a range (0.9–1.8 GHz) without specifying exact operating conditions during exposure
No additional methodological details provided in abstract (e.g., randomization/blinding, housing conditions)

View raw extracted JSON

{
  "study_type": "animal",
  "exposure": {
    "band": "RF",
    "source": "mobile phone",
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": "4 weeks"
  },
  "population": "Albino rats",
  "sample_size": 24,
  "outcomes": [
    "Histological structure changes in dorsal root ganglia (light microscopy, TEM)"
  ],
  "main_findings": "Compared with controls, exposed rats showed histological changes in dorsal root ganglia including reduced cell size, cytoplasmic condensation, peripherally located heterochromatin nucleus, loss of nucleolus, and densely packed myelinated nerve fibers. The abstract reports severity increased with higher exposure levels (80, 120, 160 missed calls/day).",
  "effect_direction": "harm",
  "limitations": [
    "Exposure quantified as number of missed calls/day rather than measured RF-EMR dose (e.g., SAR or field strength)",
    "Frequency reported as a range (0.9–1.8 GHz) without specifying exact operating conditions during exposure",
    "No additional methodological details provided in abstract (e.g., randomization/blinding, housing conditions)"
  ],
  "evidence_strength": "low",
  "confidence": 0.78,
  "peer_reviewed_likely": "unknown",
  "keywords": [
    "RF-EMR",
    "mobile phone radiation",
    "GSM",
    "0.9 GHz",
    "1.8 GHz",
    "dorsal root ganglion",
    "albino rats",
    "histology",
    "TEM",
    "dose-dependent"
  ],
  "suggested_hubs": [
    {
      "slug": "rf-mobile-phones",
      "weight": 0.9,
      "reason": "Animal study assessing GSM mobile phone RF-EMR exposure effects."
    }
  ]
}

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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.9734/jpri/2021/v33i1331266
PubMed: Not supplied

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