Electromagnetic interactions in regulations of cell behaviors and morphogenesis
← Research streamThe article summarizes emerging evidence that cellular electromagnetic fields and inter-/intracellular electromagnetic interactions (including those associated with biomolecular oscillations and centrosomes/microtubules) are implicated in regulating cell beha…
Study snapshot
Abstract
Electromagnetic interactions in regulations of cell behaviors and morphogenesis Sun G, Li J, Zhou W, Hoyle RG, Zhao Y. Electromagnetic interactions in regulations of cell behaviors and morphogenesis. Front Cell Dev Biol. 2022;10:1014030. Published 2022 Oct 19. doi:10.3389/fcell.2022.1014030 Abstract Emerging evidence indicates that the cellular electromagnetic field regulates the fundamental physics of cell biology. The electromagnetic oscillations and synchronization of biomolecules triggered by the internal and external pulses serve as the physical basis of the cellular electromagnetic field. Recent studies have indicated that centrosomes, a small organelle in eukaryotic cells that organize spindle microtubules during mitosis, also function as a nano-electronic generator in cells. Additionally, cellular electromagnetic fields are defined by cell types and correlated to the epigenetic status of the cell. These interactions between tissue-specific electromagnetic fields and chromatin fibers of progenitor cells regulate cell differentiation and organ sizes. The same mechanism is implicated in the regulation of tissue homeostasis and morphological adaptation in evolution. Intercellular electromagnetic interactions also regulate the migratory behaviors of cells and the morphogenesis programs of neural circuits. The process is closely linked with centrosome function and intercellular communication of the electromagnetic fields of microtubule filaments. Clearly, more and more evidence has shown the importance of cellular electromagnetic fields in regulatory processes. Furthermore, a detailed understanding of the physical nature of the inter- and intracellular electromagnetic interactions will better our understanding of fundamental biological questions and a wide range of biological processes. Open access paper: ncbi.nlm.nih.gov
AI evidence extraction
Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.
Main findings
The article summarizes emerging evidence that cellular electromagnetic fields and inter-/intracellular electromagnetic interactions (including those associated with biomolecular oscillations and centrosomes/microtubules) are implicated in regulating cell behaviors, differentiation, organ size, tissue homeostasis, migration, and morphogenesis programs.
Outcomes measured
- cell behaviors
- morphogenesis
- cell differentiation
- organ size regulation
- tissue homeostasis
- migratory behaviors of cells
- neural circuit morphogenesis
- epigenetic status/chromatin interactions
View raw extracted JSON
{
"study_type": "review",
"exposure": {
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"source": null,
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"outcomes": [
"cell behaviors",
"morphogenesis",
"cell differentiation",
"organ size regulation",
"tissue homeostasis",
"migratory behaviors of cells",
"neural circuit morphogenesis",
"epigenetic status/chromatin interactions"
],
"main_findings": "The article summarizes emerging evidence that cellular electromagnetic fields and inter-/intracellular electromagnetic interactions (including those associated with biomolecular oscillations and centrosomes/microtubules) are implicated in regulating cell behaviors, differentiation, organ size, tissue homeostasis, migration, and morphogenesis programs.",
"effect_direction": "unclear",
"limitations": [],
"evidence_strength": "insufficient",
"confidence": 0.66,
"peer_reviewed_likely": "yes",
"keywords": [
"cellular electromagnetic field",
"electromagnetic oscillations",
"synchronization",
"centrosome",
"microtubules",
"chromatin",
"epigenetics",
"cell differentiation",
"morphogenesis",
"cell migration",
"neural circuits"
],
"suggested_hubs": []
}AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.
Identifiers and source
DOI: 10.3389/fcell.2022.1014030
PubMed: Not supplied
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