Effects of Heat and WiFi (2.4 GHz) Exposure on Rat Cardiovascular System

2022 · Harm · Low evidence

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HarmLow evidencePaper 654

Compared with controls, the WiFi-exposed group had increased heart weight and increased myocardium volume density (P < 0.05). WiFi exposure was also associated with higher MDA and lower TAC and GSH versus control (P < 0.05).

Study snapshot

Publicationmanual · 2022

Study typeanimal

Reported directionHarm

Evidence ratingLow

Abstract

Effects of Heat and WiFi (2.4 GHz) Exposure on Rat Cardiovascular System Jafari M, Masoudi E, Sotoudeh N, Hosseini S F. Effects of Heat and WiFi (2.4 GHz) Exposure on Rat Cardiovascular System. Health Scope. 2022;11(3):e120282. doi:10.5812/jhealthscope-120282 Abstract Background: Today, wireless communication systems are destructive with increased lipid peroxidation and oxidation state and have adverse biological effects on human health. Objectives: In this study, we examined the effects of exposure to WiFi wireless frequency (2.4 GHz) on histopathological changes in the cardiovascular system of rats. Methods: The experimental groups included 32 adult male rats divided into control (not exposed to heat and WiFi), WiFi (exposed to 2.45 GHz for 52 consecutive days (2 h/day)), heat (water bath of 43°C for 52 consecutive days (10 min/day)), and heat+WiFi groups (exposed to 2.45 GHz then water bath of 43°C). On the 52nd day, the heart was removed, and its total volume and weight were determined using stereological techniques. The number of cardiomyocytes nuclei and the volume of the myocardium were determined. Blood samples were collected to measure reduced glutathione (GSH) content, Total Antioxidant Capacity (TAC), and malondialdehyde level (MDA). Data were analyzed by ANOVA, Kruskal-Wallis, and Mann-Whitney U tests. Results: The heart weight and volume density of the myocardium increased in the WiFi-irradiated group compared to the control group (P < 0.05). Also, exposure to WiFi increased MDA levels and decreased TAC and GSH compared to the control group (P < 0.05). Conclusions: This study indicated that RFW might cause structural changes and oxidative stress in the heart. Also, exposure to radiofrequency decreased total antioxidant activity in heart tissue with histological changes, including myocardium hypertrophy and decreased number of myocytes. Open access paper: brieflands.com

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeanimal

Effect directionharm

Population32 adult male rats

Sample size32

ExposureRF · 2450 MHz · 52 consecutive days (2 h/day)

Evidence strengthLowConfidence: 78% · Peer reviewed: unknown

Main findings

Outcomes measured

Heart weight
Heart total volume (stereology)
Volume density of myocardium
Number of cardiomyocyte nuclei
Myocardium volume
Reduced glutathione (GSH)
Total Antioxidant Capacity (TAC)
Malondialdehyde (MDA)
Histopathological changes in cardiovascular system/heart

Limitations

No SAR or dosimetry details reported in abstract
Animal study; generalizability to humans is uncertain
Exposure conditions for WiFi group described by frequency and duration only; intensity/power density not stated
Heat co-exposure arm present, but detailed comparative results for heat and heat+WiFi groups are not provided in the abstract

View raw extracted JSON

{
  "study_type": "animal",
  "exposure": {
    "band": "RF",
    "source": "wi-fi",
    "frequency_mhz": 2450,
    "sar_wkg": null,
    "duration": "52 consecutive days (2 h/day)"
  },
  "population": "32 adult male rats",
  "sample_size": 32,
  "outcomes": [
    "Heart weight",
    "Heart total volume (stereology)",
    "Volume density of myocardium",
    "Number of cardiomyocyte nuclei",
    "Myocardium volume",
    "Reduced glutathione (GSH)",
    "Total Antioxidant Capacity (TAC)",
    "Malondialdehyde (MDA)",
    "Histopathological changes in cardiovascular system/heart"
  ],
  "main_findings": "Compared with controls, the WiFi-exposed group had increased heart weight and increased myocardium volume density (P < 0.05). WiFi exposure was also associated with higher MDA and lower TAC and GSH versus control (P < 0.05).",
  "effect_direction": "harm",
  "limitations": [
    "No SAR or dosimetry details reported in abstract",
    "Animal study; generalizability to humans is uncertain",
    "Exposure conditions for WiFi group described by frequency and duration only; intensity/power density not stated",
    "Heat co-exposure arm present, but detailed comparative results for heat and heat+WiFi groups are not provided in the abstract"
  ],
  "evidence_strength": "low",
  "confidence": 0.78,
  "peer_reviewed_likely": "unknown",
  "keywords": [
    "WiFi",
    "2.4 GHz",
    "2.45 GHz",
    "radiofrequency",
    "rats",
    "cardiovascular system",
    "heart",
    "myocardium",
    "oxidative stress",
    "malondialdehyde",
    "total antioxidant capacity",
    "glutathione",
    "histopathology",
    "heat exposure"
  ],
  "suggested_hubs": [
    {
      "slug": "school-wi-fi",
      "weight": 0.6,
      "reason": "Study evaluates biological effects of WiFi (2.4 GHz) exposure."
    }
  ]
}

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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.5812/jhealthscope-120282
PubMed: Not supplied

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